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Sitamaze M XR 50/1000 Tablet

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Biotics Lab Life Services Private Limited

Salt Composition

Sitagliptin (50mg) + Metformin (1000mg)

Overview Sitamaze M XR 50/1000 Tablet

Diabexe Duo XR 50/1000 tablets combine two medications to manage elevated blood glucose in type 2 diabetes. This dual action helps prevent serious diabetic complications like renal impairment and vision loss, potentially lowering heart attack and stroke risk. Diabexe Duo XR 50/1000 may be used alone or with other diabetes treatments, achieving optimal results when coupled with a balanced diet and regular physical activity. Dosage is individualized based on your health status, glucose levels, and other medications. Taking it with food minimizes stomach upset. Consistent daily dosing at the same time maximizes effectiveness; discontinuation should only occur under your physician's guidance. Adherence to your prescribed diet and exercise regimen is crucial. Lifestyle significantly impacts diabetes management. Common side effects include nausea, vomiting, diarrhea, stomach discomfort, headache, and throat irritation. Low blood sugar (hypoglycemia) is a potential risk, especially with concurrent use of insulin or sulfonylureas; learn how to identify and manage this. This medication isn't for everyone. Inform your doctor of any pre-existing kidney, liver, or heart conditions, pancreatic issues, or significant alcohol consumption before starting. Pregnant or lactating individuals should consult their doctor. Interactions with other medications are possible; disclose all medications to ensure safety. Alcohol should be limited due to its blood glucose-lowering effect. Your doctor will monitor kidney function and blood sugar levels throughout treatment.

Uses of Sitamaze M XR 50/1000 Tablet

Managing Type 2 Diabetes

Major Benefits of Sitamaze M XR 50/1000 Tablet:

Consume this medication precisely as your physician directs, adhering to both the prescribed dosage and duration. Ingest the Sitamaze M XR 50/1000 Tablet whole; avoid chewing, crushing, or fracturing it. Administer this medication with a meal.

Common Side effects of Sitamaze M XR 50/1000 Tablet:

  • Decreased appetite
  • Vomiting
  • Upper respiratory tract infection
  • Hypoglycemia (low blood glucose level)
  • Abdominal bloating
  • Nausea
  • Diarrhea

How to use Sitamaze M XR 50/1000 Tablet:

Administer this medication precisely as your physician directs, adhering to the prescribed dosage and treatment length. Ingest the Sitamaze M XR 50/1000 Tablet whole; avoid chewing, crushing, or breaking it. Consume this medication with food.

How Sitamaze M XR 50/1000 Tablet works:

Sitamaze M XR 50/1000 tablets contain sitagliptin and metformin, working synergistically to manage blood glucose. Sitagliptin enhances insulin production by the pancreas, improves insulin utilization, and diminishes hepatic glucose output. Metformin, a biguanide, reduces liver glucose production, slows intestinal glucose absorption, and increases insulin sensitivity. This combined action leads to superior glycemic control.

SAFETY ADVICE

AlcoholAlcoholUNSAFE

Concurrent use of Sitamaze M XR 50/1000 Tablet and alcohol is contraindicated.

PregnancyPregnancyCONSULT YOUR DOCTOR

The use of Sitamaze M XR 50/1000 Tablet during pregnancy may pose risks. While human data is scarce, animal research indicates potential harm to a fetus. A physician will assess the advantages against possible dangers prior to prescribing. Seek medical advice before taking this medication.

Breast feedingBreast feedingCONSULT YOUR DOCTOR

The use of Sitamaze M XR 50/1000 tablets while breastfeeding is likely inadvisable. Available human data indicate a potential for the medication to transfer to breast milk, posing a risk to the infant.

DrivingDrivingCAUTION

Impaired driving is possible with either hypoglycemia or hyperglycemia. Refrain from driving if you experience these conditions.

KidneyKidneyCAUTION

Patients with impaired kidney function should use Sitamaze M XR 50/1000 Tablets cautiously, potentially requiring dosage modification. Severe kidney disease contraindicates the use of Sitamaze M XR 50/1000 Tablets. Physician consultation is essential. Regular kidney function monitoring is recommended during treatment.

LiverLiverUNSAFE

Use of Sitamaze M XR 50/1000 tablets is likely inadvisable for individuals with hepatic impairment and should be avoided. Medical advice is recommended.

What if you forget to take Sitamaze M XR 50/1000 Tablet :

Should you forget to take a Sitamaze M XR 50/1000 Tablet, administer it immediately upon remembering. Nevertheless, if your next scheduled dose is imminent, omit the missed dose and resume your usual medication timetable. Avoid taking a double dose.

Facts to Know About Sitamaze M XR 50/1000 Tablet

LabelValue
Potential for Dependence None.
Type of Medication Medication for diabetes

FAQs on Sitamaze M XR 50/1000 Tablet

Sitagliptin and Metformin, combined as Sitamaze M XR 50/1000 Tablet, manage type 2 diabetes mellitus in adults. This medication enhances blood sugar control when coupled with a healthy diet and regular physical activity. Metformin reduces hepatic glucose production and improves insulin responsiveness. Sitagliptin works by suppressing DPP-4, thereby boosting pancreatic insulin secretion. This formulation is unsuitable for individuals under 18.
Prolonged Sitamaze M XR 50/1000 Tablet use can indeed lead to vitamin B12 deficiency by disrupting its intestinal absorption. This deficiency, if left unaddressed, may result in anemia and neurological complications. Symptoms can include peripheral numbness and tingling, muscle weakness, urinary dysfunction, cognitive changes, and gait instability. To mitigate this risk, supplemental vitamin B12 is recommended by some experts at least annually.
Sitamaze M XR 50/1000 Tablet may cause common adverse reactions including low blood sugar (hypoglycemia), taste disturbances, nausea, abdominal pain, diarrhea, headache, and upper respiratory infections. Serious, though infrequent, side effects such as lactic acidosis are also possible. Prolonged treatment may result in vitamin B12 deficiency.
Patients with hypersensitivity to Sitamaze M XR 50/1000 Tablet constituents or inactive ingredients should not use this medication. Its administration is contraindicated in individuals with severe renal or hepatic dysfunction, congestive cardiac failure, lactic acidosis, or diabetic ketoacidosis.
Combining Sitamaze M XR 50/1000 Tablet with alcohol is unsafe due to the heightened risk of lactic acidosis.
Maintain this medication within its original, securely sealed container or packaging. Follow the storage guidelines printed on the packaging or label. Discard any remaining medication. Prevent access by children, pets, and other individuals.
Indeed, Sitamaze M XR 50/1000 Tablets may cause lactic acidosis, a serious medical condition characterized by excessive blood lactic acid. Also termed MALA (Metformin-associated lactic acidosis), this uncommon adverse reaction linked to metformin is contraindicated in individuals with pre-existing kidney impairment, advanced age, or significant alcohol consumption. Symptoms such as muscular discomfort or weakness, vertigo, fatigue, cold extremities, dyspnea, nausea, emesis, abdominal pain, or bradycardia warrant immediate cessation of Sitagliptin + Metformin and prompt medical attention.
Sitamaze M XR 50/1000 tablets contain sitagliptin and metformin, working synergistically to manage type 2 diabetes mellitus in adults. This medication enhances glycemic control when combined with a healthy diet and regular physical activity. Metformin reduces hepatic glucose production and improves insulin responsiveness. Sitagliptin's mechanism involves DPP4 enzyme inhibition, leading to increased pancreatic insulin secretion. This formulation is unsuitable for individuals under 18 years old.
Sitamaze M XR 50/1000 Tablet may cause common adverse reactions including hypoglycemia, taste disturbances, nausea, abdominal discomfort, diarrhea, headache, and upper respiratory infections. Rare, but potentially severe, side effects such as lactic acidosis may occur. Prolonged treatment may result in vitamin B12 deficiency.
Patients with hypersensitivity to Sitamaze M XR 50/1000 Tablet constituents or inactive ingredients should not use this medication. Similarly, its use is contraindicated in individuals with severely compromised kidney or liver function, congestive heart failure, lactic acidosis, or diabetic ketoacidosis.
Combining Sitamaze M XR 50/1000 tablets with alcohol is unsafe and may heighten the risk of lactic acidosis.
Lactic acidosis, a serious medical condition characterized by excessive blood lactic acid, is a potential consequence of Sitamaze M XR 50/1000 Tablet use. This complication, also termed Metformin-associated lactic acidosis (MALA), is infrequent but necessitates caution. Therefore, its use is contraindicated in individuals with pre-existing kidney impairment, the elderly, or those consuming significant quantities of alcohol. Presenting symptoms might encompass muscular discomfort or weakness, vertigo, fatigue, peripheral coldness, respiratory distress, nausea, emesis, abdominal pain, or bradycardia. Should these symptoms arise, discontinue Sitagliptin + Metformin immediately and seek urgent medical attention.
Prolonged Sitamaze M XR 50/1000 Tablet use can indeed lead to Vitamin B12 deficiency due to impaired absorption in the gastrointestinal tract. This deficiency, if left unaddressed, may manifest as anemia, neurological complications including paresthesia in the extremities, generalized weakness, urinary dysfunction, cognitive changes, and ataxia. Therefore, supplemental Vitamin B12 is recommended annually by some experts to mitigate these potential adverse effects.
Retain this medication within its original, sealed container. Follow the storage guidelines provided on the packaging. Discard any remaining medication. Prevent access by children, pets, and other individuals.
Sitagliptin and Metformin, combined as Sitamaze M XR 50/1000 Tablet, treat type 2 diabetes mellitus in adults. This medication enhances blood sugar control when coupled with a healthy diet and exercise regimen. Metformin reduces liver glucose production and boosts insulin sensitivity. Sitagliptin works by suppressing DPP4, thus promoting increased pancreatic insulin secretion. This formulation is unsuitable for individuals under 18.
Sitamaze M XR 50/1000 Tablet may cause common side effects including low blood sugar (hypoglycemia), taste changes, nausea, abdominal pain, diarrhea, headache, and upper respiratory infections. Rare but potentially serious adverse reactions such as lactic acidosis may occur. Prolonged treatment might result in vitamin B12 deficiency.
Patients with hypersensitivity to Sitamaze M XR 50/1000 Tablet constituents or inactive ingredients should not use this medication. Similarly, its use is contraindicated in individuals with severely compromised renal or hepatic function, congestive heart failure, lactic acidosis, or diabetic ketoacidosis.
Combining Sitamaze M XR 50/1000 Tablet and alcohol is unsafe due to a heightened risk of lactic acidosis.
Lactic acidosis, a serious medical condition characterized by excessive blood lactic acid, is a potential complication of Sitamaze M XR 50/1000 Tablet use. This rare adverse effect, also termed Metformin-associated lactic acidosis (MALA), necessitates avoidance in individuals with impaired kidney function, advanced age, or significant alcohol consumption. Symptoms such as muscular discomfort or weakness, vertigo, fatigue, cold extremities, respiratory distress, nausea, emesis, abdominal pain, and bradycardia warrant immediate discontinuation of Sitagliptin + Metformin and prompt medical attention.
Prolonged Sitamaze M XR 50/1000 Tablet use can indeed lead to Vitamin B12 deficiency by disrupting its gastrointestinal absorption. This deficiency, if left unaddressed, may result in anemia and neurological complications, manifesting as peripheral numbness and tingling, muscle weakness, urinary dysfunction, cognitive changes, and gait instability. Preventive measures, according to some studies, include annual supplemental Vitamin B12 intake.
Retain this medication in its original, securely sealed container. Follow the storage guidelines provided on the packaging or label. Discard any leftover medication. Prevent access by children, pets, and others.
Sitamaze M XR 50/1000 Tab...
111
MRP 129
13% off