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Sitazit-M ER 1000 Tablet

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Prescription Required

Marketer

Glenmark Pharmaceuticals Ltd

Salt Composition

Sitagliptin (100mg) + Metformin (1000mg)

Overview Sitazit-M ER 1000 Tablet

Duo-Met XR 1000mg tablets combine two medications to manage elevated blood glucose in type 2 diabetes. This dual action helps prevent serious diabetic complications like vision loss and kidney disease, potentially lowering heart attack and stroke risk. Duo-Met XR 1000mg may be used alone or with other diabetes treatments; optimal results require adherence to a healthy diet and regular physical activity. Dosage is personalized based on your health, blood sugar readings, and other medications. Taking it with food minimizes stomach upset. Consistent daily dosing at the same time maximizes effectiveness; discontinue only under your doctor's guidance. Maintaining the prescribed diet and exercise plan is crucial for diabetes control; lifestyle significantly impacts management. Common side effects include nausea, diarrhea, vomiting, indigestion, headache, and sore throat. Low blood sugar (hypoglycemia) is possible, especially with insulin or sulfonylurea use; learn its signs and treatment. This medication isn't suitable for everyone. Inform your physician of any pre-existing kidney, liver, heart, or pancreatic issues, or significant alcohol consumption before starting. Pregnant or breastfeeding individuals should seek medical advice. Interactions with other medications are possible; disclose all medications to your doctor. Alcohol should be limited due to its blood glucose-lowering effect. Your doctor will monitor kidney function and blood sugar levels throughout treatment.

Uses of Sitazit-M ER 1000 Tablet

Managing type 2 diabetes

Major Benefits of Sitazit-M ER 1000 Tablet:

Consume this medication precisely as your physician directs, adhering to both the prescribed dosage and treatment length. Ingest the tablet whole; avoid chewing, crushing, or fracturing it. Take Sitazit-M ER 1000 Tablet with a meal.

Common Side effects of Sitazit-M ER 1000 Tablet:

  • Decreased appetite
  • Vomiting
  • Upper respiratory tract infection
  • Hypoglycemia (low blood glucose level)
  • Abdominal bloating
  • Nausea
  • Diarrhea

How to use Sitazit-M ER 1000 Tablet:

Consume this medication according to your physician's prescribed dosage and timeframe. Ingest the tablet whole; avoid chewing, crushing, or fracturing it. It is recommended to take Sitazit-M ER 1000 Tablet with a meal.

How Sitazit-M ER 1000 Tablet works:

Sitagliptin and metformin, combined as Sitazit-M ER 1000 Tablet, work synergistically to manage blood glucose. Sitagliptin boosts insulin production by the pancreas, improves insulin utilization, and lessens hepatic glucose output. Metformin, a biguanide, reduces liver glucose production, slows intestinal glucose absorption, and enhances insulin sensitivity. This dual action results in superior glycemic control.

SAFETY ADVICE

AlcoholAlcoholUNSAFE

Combining alcohol and Sitazit-M ER 1000 Tablets poses a significant safety risk.

PregnancyPregnancyCONSULT YOUR DOCTOR

The use of Sitazit-M ER 1000 Tablet during pregnancy may pose risks. While human data is scarce, animal research indicates potential harm to the fetus. A physician will assess the advantages against possible risks prior to prescribing. Seek medical advice.

Breast feedingBreast feedingCONSULT YOUR DOCTOR

Extended-release Sitazit-M 1000 mg tablets are likely not safe for use while breastfeeding. Available human data indicates potential transfer of the medication into breast milk, posing a risk to the infant.

DrivingDrivingCAUTION

Driving ability can be impaired by both hypoglycemia and hyperglycemia. Refrain from driving if you experience these conditions.

KidneyKidneyCAUTION

Patients with kidney impairment should use Sitazit-M ER 1000 Tablets cautiously, potentially requiring dosage modification. Physician consultation is recommended. Sitazit-M ER 1000 Tablets are contraindicated in patients with severe kidney disease. Regular kidney function monitoring is advised during treatment.

LiverLiverUNSAFE

Use of Sitazit-M ER 1000 Tablet is likely inadvisable for individuals with hepatic impairment and should be omitted. Physician consultation is recommended.

What if you forget to take Sitazit-M ER 1000 Tablet :

Should you forget a dose of Sitazit-M ER 1000 Tablet, administer it promptly. Nevertheless, if your next scheduled dose is imminent, omit the missed dose and resume your usual dosing regimen. Avoid taking a double dose.

Facts to Know About Sitazit-M ER 1000 Tablet

LabelValue
Developing Habits No.
Treatment Category Diabetes Management

FAQs on Sitazit-M ER 1000 Tablet

Sitazit-M ER 1000 Tablet combines sitagliptin and metformin to manage type 2 diabetes in adults. This medication improves blood sugar control when used with diet and exercise. Metformin reduces liver glucose production and enhances insulin sensitivity, while sitagliptin increases insulin release by inhibiting DPP-4. It's not suitable for individuals under 18.
Prolonged Sitazit-M ER 1000 Tablet use can lead to vitamin B12 deficiency by hindering its absorption. This deficiency may cause anemia, nerve damage (manifesting as numbness, tingling in extremities, weakness, urinary issues, cognitive changes, and ataxia), if left unaddressed. Preventive measures may include annual supplemental vitamin B12.
Sitazit-M ER 1000 Tablet may cause common side effects such as low blood sugar (hypoglycemia), altered taste, nausea, stomach pain, diarrhea, headache, and upper respiratory infections. Rare but serious side effects include lactic acidosis. Prolonged use may also result in vitamin B12 deficiency.
Sitazit-M ER 1000 Tablet is contraindicated in patients with allergies to its components or excipients, and those with severe kidney or liver impairment, congestive heart failure, lactic acidosis, or diabetic ketoacidosis.
Combining Sitazit-M ER 1000 Tablet with alcohol is unsafe and may heighten the risk of lactic acidosis.
Store this medication in its original, tightly closed container, following the storage instructions on the label. Discard any unused medication and keep it out of reach of children, pets, and others.
Sitagliptin + Metformin (Sitazit-M ER 1000 Tablet) can cause lactic acidosis (MALA), a serious medical emergency characterized by excessive blood lactic acid. This rare side effect is more likely in patients with kidney disease, the elderly, or those who consume excessive alcohol. Symptoms include muscle pain/weakness, dizziness, fatigue, cold extremities, shortness of breath, nausea, vomiting, abdominal pain, and bradycardia. If you experience these, discontinue Sitagliptin + Metformin and seek immediate medical attention.
Sitazit-M ER 1000 Tablet combines sitagliptin and metformin to treat type 2 diabetes in adults. This medication improves blood sugar control when used with a healthy diet and exercise. Metformin reduces liver glucose production and enhances insulin sensitivity, while sitagliptin increases insulin release by inhibiting DPP-4. It's not suitable for individuals under 18.
Sitazit-M ER 1000 Tablet may cause common side effects such as hypoglycemia, altered taste, nausea, stomach pain, diarrhea, headache, and upper respiratory infections. Rare but serious side effects include lactic acidosis. Prolonged use can also result in vitamin B12 deficiency.
Sitazit-M ER 1000 Tablet is contraindicated in patients with allergies to its components or excipients, and those with severe kidney or liver impairment, congestive heart failure, lactic acidosis, or diabetic ketoacidosis.
Combining alcohol and Sitazit-M ER 1000 Tablet is unsafe and may heighten the risk of lactic acidosis.
Sitagliptin + Metformin (Sitazit-M ER 1000 Tablet) can cause lactic acidosis (MALA – Metformin-associated lactic acidosis), a serious medical emergency resulting from high blood lactic acid levels. This rare side effect necessitates caution in patients with kidney disease, the elderly, or those consuming excessive alcohol. Symptoms include muscle pain/weakness, dizziness, fatigue, cold extremities, shortness of breath, nausea, vomiting, abdominal pain, and bradycardia. If these occur, discontinue Sitagliptin + Metformin and seek immediate medical attention.
Prolonged Sitazit-M ER 1000 Tablet use can lead to vitamin B12 deficiency by hindering its absorption. This deficiency may cause anemia, nerve damage (manifesting as tingling, numbness in extremities, weakness, urinary issues, cognitive changes, and ataxia), if left unaddressed. To mitigate this risk, annual supplemental vitamin B12 is recommended by some researchers.
Store this medication in its original, tightly closed container, following the storage instructions on the label. Discard any unused medication safely and ensure it's inaccessible to children, pets, and others.
Sitazit-M ER 1000 Tablet combines sitagliptin and metformin to manage type 2 diabetes in adults. This medication improves blood sugar control when used with diet and exercise. Metformin reduces liver glucose production and enhances insulin sensitivity, while sitagliptin increases insulin release by inhibiting DPP-4. It's not suitable for individuals under 18.
Sitazit-M ER 1000 Tablet may cause common side effects such as hypoglycemia, altered taste, nausea, stomach pain, diarrhea, headache, and upper respiratory infection. Rare but serious side effects include lactic acidosis. Prolonged use can also result in vitamin B12 deficiency.
Sitazit-M ER 1000 Tablets are contraindicated in patients with known allergies to its components or excipients, and those with severe kidney or liver impairment, congestive heart failure, lactic acidosis, or diabetic ketoacidosis.
Combining Sitazit-M ER 1000 Tablet with alcohol is unsafe and may heighten the risk of lactic acidosis.
Sitagliptin + Metformin (like Sitazit-M ER 1000 Tablet) can cause lactic acidosis, a serious medical emergency with high blood lactic acid levels (also known as Metformin-associated lactic acidosis or MALA). This rare side effect necessitates caution in patients with kidney disease, the elderly, or those who consume excessive alcohol. Symptoms include muscle pain/weakness, dizziness, fatigue, cold extremities, shortness of breath, nausea, vomiting, abdominal pain, and bradycardia. If you experience these, discontinue Sitagliptin + Metformin and seek immediate medical attention.
Prolonged Sitazit-M ER 1000 Tablet use can lead to vitamin B12 deficiency by hindering its absorption. This deficiency, if left untreated, may cause anemia, nerve damage (manifesting as tingling, numbness in extremities, weakness, and urinary issues), and cognitive changes (including balance problems). To mitigate this risk, annual supplemental vitamin B12 is recommended by some researchers.
Store this medication in its original, tightly closed container, following the storage instructions on the packaging. Discard any unused medication and keep it out of reach of children, pets, and others.
Sitazit-M ER 1000 Tablet
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