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Synlide-M Tablet

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Synmedic Laboratories

Salt Composition

Gliclazide (80mg) + Metformin (500mg)

Overview Synlide-M Tablet

DiabetaComb tablets are classified as antidiabetic medications. This dual-drug formulation manages type 2 diabetes in adults by regulating blood glucose. DiabetaComb should be taken with meals, consistently at the same time daily for optimal efficacy. Dosage is determined by your physician and may be adjusted based on blood sugar monitoring. Continue taking this medication, even if feeling well or experiencing controlled blood sugar, as discontinuation without medical consultation can lead to elevated blood glucose, increasing the risk of kidney complications, vision impairment, neuropathy, and limb loss. This medication is part of a comprehensive treatment plan encompassing a healthy diet, regular physical activity, and weight management as directed by your doctor. Lifestyle choices significantly impact diabetes control. Common side effects include hypoglycemia (low blood sugar), characterized by sweating, dizziness, headache, and tremors; constipation; and vomiting. Maintain regular mealtimes and carry a rapid-acting glucose source (e.g., sugary snacks, fruit juice) to counteract hypoglycemia. Alcohol consumption should be limited due to its potential to exacerbate low blood sugar. Additional potential side effects include altered taste, nausea, diarrhea, abdominal pain, headache, and upper respiratory infections. Weight gain may occur. Do not use if you have type 1 diabetes, diabetic ketoacidosis, or severe kidney or liver impairment. Inform your physician of any history of heart disease before commencing treatment; DiabetaComb may be unsuitable in such cases. Pregnant or breastfeeding individuals should seek medical advice prior to use. Regular blood glucose monitoring is essential, and your doctor may order blood tests to assess blood cell counts and liver function.

Uses of Synlide-M Tablet

Adult-onset diabetes

Major Benefits of Synlide-M Tablet:

Consume this medication precisely as directed by your physician, adhering to the prescribed dosage and treatment period. Ingest the tablet whole; avoid chewing, crushing, or fracturing it. It's recommended to take Synlide-M Tablet with food.

Common Side effects of Synlide-M Tablet:

  • Hypoglycemia (low blood glucose level)
  • Headache
  • Dizziness
  • Diarrhea
  • Upper respiratory tract infection
  • Nausea
  • Flatulence
  • Constipation

How to use Synlide-M Tablet:

Consume this medication precisely as your physician directs, adhering to both the prescribed dosage and treatment length. Ingest the tablet whole; avoid chewing, crushing, or fracturing it. It's recommended to take Synlide-M Tablet with a meal.

How Synlide-M Tablet works:

Gliclazide and metformin are combined in Synlide-M tablets to manage blood sugar levels.

SAFETY ADVICE

AlcoholAlcoholUNSAFE

Consuming alcohol alongside Synlide-M Tablet is inadvisable.

PregnancyPregnancyCONSULT YOUR DOCTOR

Using Synlide-M tablets during pregnancy poses a confirmed risk to the fetus. Therefore, it's not recommended. In exceptional, life-threatening circumstances, a physician might prescribe it if the potential advantages outweigh the known hazards. Always seek medical advice.

Breast feedingBreast feedingCONSULT YOUR DOCTOR

Use of Synlide-M Tablet while breastfeeding is likely inadvisable. Available human data indicates potential transfer to breast milk, posing a possible risk to the infant.

DrivingDrivingCAUTION

Impaired driving is possible with excessively low or high blood sugar levels. Refrain from driving if you experience such symptoms.

KidneyKidneyCAUTION

Patients with kidney impairment should use Synlide-M Tablets cautiously, potentially requiring dosage modification. Severe kidney disease contraindicates Synlide-M Tablet use. Physician consultation is essential. Regular kidney function monitoring is advised during treatment.

LiverLiverCAUTION

Patients with liver impairment should exercise caution when using Synlide-M Tablets, potentially requiring dosage modification. A physician's consultation is advised. For those with mild to moderate liver disease, Synlide-M Tablets are typically initiated at a low dose; however, their use is contraindicated in patients with severe hepatic dysfunction.

What if you forget to take Synlide-M Tablet :

Should you forget a Synlide-M Tablet dose, take it immediately. However, if your next dose is imminent, omit the missed dose and resume your usual dosing regimen. Avoid taking a double dose.

Facts to Know About Synlide-M Tablet

LabelValue
Developing Habits No.
Treatment Category Diabetes Management

FAQs on Synlide-M Tablet

Synlide-M tablets combine gliclazide and metformin to manage type 2 diabetes mellitus in adults. This combination improves blood sugar control when used with diet and exercise. Gliclazide stimulates insulin release from the pancreas, while metformin reduces liver glucose production and enhances insulin sensitivity. It's not suitable for type 1 diabetes.
Synlide-M Tablet may cause common side effects such as low blood sugar (hypoglycemia), altered taste, nausea, stomach pain, diarrhea, headache, and upper respiratory infection. Rare but serious side effects, including lactic acidosis, are also possible. Prolonged use may result in vitamin B12 deficiency.
Synlide-M Tablets can cause low blood sugar (hypoglycemia), manifesting as nausea, headache, irritability, hunger, sweating, dizziness, rapid heartbeat, and shakiness or anxiety. This risk increases with missed meals, alcohol consumption, excessive exercise, or concurrent use of other diabetes medications. Therefore, regular blood sugar monitoring is crucial. Carry glucose tablets, honey, or fruit juice for emergencies.
Synlide-M Tablet can cause lactic acidosis, a serious medical emergency characterized by high blood lactic acid levels (also known as MALA, or Metformin-associated lactic acidosis). This rare side effect is more likely in patients with kidney disease, older adults, or those who consume excessive alcohol. Symptoms include muscle pain/weakness, dizziness, fatigue, cold extremities, shortness of breath, nausea, vomiting, abdominal pain, and bradycardia. If you experience these, discontinue Synlide-M and seek immediate medical attention.
Prolonged Synlide-M Tablet use can lead to vitamin B12 deficiency by hindering its absorption in the stomach. This deficiency, if left untreated, may result in anemia, neurological issues such as tingling, numbness in extremities, weakness, urinary problems, cognitive changes, and balance difficulties (ataxia). To mitigate this risk, supplemental vitamin B12 intake at least annually is recommended by some researchers.
Synlide-M Tablets are contraindicated in patients with allergies to any ingredient or excipient. They should also be avoided in those with moderate to severe kidney disease or metabolic acidosis, including diabetic ketoacidosis.
Combining Synlide-M Tablet and alcohol is unsafe. Alcohol can worsen low blood sugar and raise the risk of lactic acidosis.
Synlide-M Tablet combines gliclazide and metformin to manage type 2 diabetes mellitus in adults. It enhances blood glucose control when used with diet and exercise. Gliclazide stimulates insulin release from the pancreas, while metformin reduces liver glucose production and improves insulin sensitivity. This combination is unsuitable for type 1 diabetes.
Synlide-M Tablet may cause common side effects such as low blood sugar (hypoglycemia), altered taste, nausea, stomach pain, diarrhea, headache, and upper respiratory infections. Rare but serious side effects, including lactic acidosis, are also possible. Prolonged use may result in vitamin B12 deficiency.
Synlide-M Tablets can cause low blood sugar (hypoglycemia), manifesting as nausea, headache, irritability, hunger, sweating, dizziness, rapid heartbeat, anxiety, or shakiness. This risk increases with missed meals, alcohol consumption, excessive exercise, or concurrent use of other diabetes medications. Therefore, regular blood sugar monitoring is crucial. Carry glucose tablets, honey, or fruit juice for emergencies.
Synlide-M Tablet can cause lactic acidosis, a serious medical emergency characterized by high blood lactic acid levels (also known as MALA, or Metformin-associated lactic acidosis). This rare side effect is more likely in patients with kidney disease, older adults, or those who consume excessive alcohol. Symptoms include muscle pain or weakness, dizziness, fatigue, cold extremities, shortness of breath, nausea, vomiting, abdominal pain, and slow heart rate. If you experience these, discontinue Synlide-M immediately and seek medical attention.
Prolonged Synlide-M Tablet use can lead to vitamin B12 deficiency by interfering with its stomach absorption. This deficiency, if left untreated, may cause anemia, nerve damage (manifesting as tingling, numbness in extremities, weakness), urinary issues, cognitive changes, and balance problems (ataxia). To mitigate this risk, annual supplemental vitamin B12 intake is recommended by some researchers.
Synlide-M Tablets are contraindicated in patients with allergies to any ingredient or excipient, and in those with moderate to severe kidney disease or metabolic acidosis, including diabetic ketoacidosis.
Combining Synlide-M Tablet and alcohol is unsafe. This combination may worsen low blood sugar and raise the risk of lactic acidosis.
Synlide-M Tablet
56
MRP 65
13% off