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Trigem 1 Tablet

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Prescription Required

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Medley Pharmaceuticals

Salt Composition

Glimepiride (1mg) + Metformin (500mg) + Pioglitazone (15mg)

Overview Trigem 1 Tablet

Combiflex-1 is a dual-action oral medication formulated to manage blood glucose. This medication complements a healthy diet and regular exercise to optimize glycemic control in adult patients with type 2 diabetes. It enhances insulin effectiveness, resulting in reduced blood sugar. Always adhere to your physician's prescribed dosage and regimen for Combiflex-1. Administer this medication with food to minimize gastrointestinal discomfort. If a dose is missed, take it promptly; however, if the next dose is imminent, omit the missed dose and resume your usual schedule. Never double the dose. An overdose can cause dangerously low blood sugar (hypoglycemia). Concurrent use with other antidiabetic medications, alcohol consumption, or meal skipping may precipitate hypoglycemia. Regular blood sugar monitoring is crucial during treatment. Commonly reported adverse effects include nausea, diarrhea, abdominal pain, headache, bone fractures, and respiratory infections. Prior to initiating Combiflex-1, disclose any pre-existing kidney, liver, or heart conditions to your doctor. Pregnant or lactating individuals should seek medical counsel before commencing treatment. Renal function assessments will be conducted before treatment begins. Limit alcohol consumption during therapy to mitigate potential side effects.

Primary Ingredients of Trigem 1 Tablet

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Uses of Trigem 1 Tablet

Managing type 2 diabetes

Major Benefits of Trigem 1 Tablet:

Consume this medication according to your physician's prescribed dosage and schedule. Ingest the tablet whole; avoid chewing, crushing, or fracturing it. Administer Trigem 1 Tablet with a meal.

Common Side effects of Trigem 1 Tablet:

  • Hypoglycemia (low blood glucose level)
  • Headache
  • Nausea
  • Diarrhea
  • Dizziness
  • Vomiting
  • Anemia (low number of red blood cells)
  • Weakness
  • Sinus infection

How to use Trigem 1 Tablet:

Consume this medication precisely as directed by your physician, adhering to the prescribed dosage and timeframe. Ingest the Trigem 1 Tablet whole; avoid chewing, crushing, or fracturing it. It should be taken with a meal.

How Trigem 1 Tablet works:

Trigem 1 Tablet combines glimepiride, metformin, and pioglitazone—three distinct antidiabetic agents—to optimize blood sugar management when single or dual drug regimens prove insufficient. Glimepiride, a sulfonylurea, stimulates pancreatic insulin secretion, thus reducing blood glucose levels. Metformin, a biguanide, acts through multiple pathways: decreasing hepatic glucose production, slowing intestinal glucose absorption, and enhancing insulin responsiveness. Finally, pioglitazone, a thiazolidinedione, further improves insulin sensitivity.

SAFETY ADVICE

AlcoholAlcoholUNSAFE

Alcohol consumption alongside Trigem 1 Tablet is inadvisable.

PregnancyPregnancyCONSULT YOUR DOCTOR

Using Trigem 1 Tablet during pregnancy might pose risks. While human research is scarce, animal studies indicate potential harm to the unborn child. A physician will assess the advantages against possible dangers prior to prescribing. Seek medical advice.

Breast feedingBreast feedingCONSULT YOUR DOCTOR

There is likely a risk associated with using Trigem 1 Tablet while breastfeeding. Available human data indicates potential transfer of the medication into breast milk, posing a possible threat to the infant.

DrivingDrivingCAUTION

Driving ability can be impaired by both hypoglycemia and hyperglycemia. Refrain from driving if you experience these conditions.

KidneyKidneyCAUTION

Patients with kidney impairment should exercise caution when using Trigem 1 Tablet, potentially requiring dosage modification. Severe kidney disease contraindicates Trigem 1 Tablet use. Physician consultation is recommended. Regular assessment of renal function is advised during treatment.

LiverLiverCAUTION

Individuals with hepatic impairment should exercise caution when using Trigem 1 Tablet, as dose modification may be necessary. Consult a physician before use. Trigem 1 Tablet is contraindicated in patients exhibiting severe liver dysfunction.

What if you forget to take Trigem 1 Tablet :

Should you forget a Trigem 1 Tablet dose, take it immediately. If, however, your next dose is imminent, omit the missed dose and resume your usual dosing regimen. Never take a double dose.

Facts to Know About Trigem 1 Tablet

LabelValue
Developing Habits No.
Treatment Category Diabetes Management

FAQs on Trigem 1 Tablet

Consuming alcohol while taking Trigem 1 Tablet is unsafe. Alcohol can cause dangerously low blood sugar (hypoglycemia) and raise the risk of lactic acidosis.
Consult your doctor before taking Trigem 1 Tablet if you have congestive heart failure, kidney or liver problems, or eye swelling. Also inform your doctor if you are pregnant, breastfeeding, or premenopausal, and about all medications you are taking, including prescription and non-prescription drugs, vitamins, and herbal supplements.
Metformin, a component of Trigem 1 Tablet, can lead to vitamin B12 deficiency with prolonged use due to impaired vitamin B12 absorption in the stomach.
Trigem 1 Tablets can cause hypoglycemia (low blood sugar). Symptoms include nausea, headache, irritability, hunger, sweating, dizziness, rapid heart rate, and anxiety or shakiness. These are more likely if you skip meals, drink alcohol, overexert yourself, or take other diabetes medication. Regular blood sugar monitoring is crucial. Always carry a sugary treat, such as candy or chocolate.
Store this medication in its original, tightly closed container, as directed on the packaging. Discard any unused medication. Keep it out of reach of children, pets, and others.
Trigem 1 Tablet
114
MRP 133
13% off