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Twinculor 450mg/300mg Tablet

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Prescription Required

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TOSC International Pvt Ltd

Salt Composition

Rifampicin (450mg) + Isoniazid (300mg)

Overview Twinculor 450mg/300mg Tablet

Combiflora 450mg/300mg tablets combat tuberculosis by inhibiting the growth of causative bacteria. This prescription medication, administered as directed by your physician, should be taken on an empty stomach at a consistent time for optimal effectiveness. Exceeding the prescribed dosage can be harmful. Missed doses should be taken promptly upon recollection. Complete the entire course of treatment, even with symptom improvement; premature cessation may reduce efficacy. Therapeutic effects may take time to manifest. Consult your doctor if symptoms worsen or fail to improve. Common side effects include nausea, vomiting, fever, dark urine, sweating, increased salivation, etc. Hydration is crucial to manage these. Severe side effects are uncommon, but immediate medical attention is needed for allergic reactions (rashes, itching, swelling, breathing difficulties). Inform your physician of all other medications before commencing treatment. Patients with liver or kidney disease require careful monitoring. Pregnant or breastfeeding individuals should seek medical advice prior to use. Alcohol should be avoided due to potential drowsiness. While generally non-impairing, avoid driving if drowsiness or dizziness occurs. Maintain adequate rest and a nutritious diet for faster recovery. Your doctor may order blood tests and other diagnostics to assess the medication's impact.

Uses of Twinculor 450mg/300mg Tablet

Managing Tuberculosis (TB) Infection

Major Benefits of Twinculor 450mg/300mg Tablet:

Administer this medication precisely as your physician directs, adhering to the prescribed dosage and timeframe. Ingest the 450mg/300mg Twinculor tablet whole; avoid chewing, crushing, or fracturing it. Consumption should occur on an empty stomach. Refrain from consuming Twinculor 450mg/300mg tablets concurrently with tyramine-rich foods, including certain cheeses, smoked seafood, meats, and some beers.

Common Side effects of Twinculor 450mg/300mg Tablet:

  • Dark colored urine
  • Rash
  • Vomiting
  • Jaundice
  • Fever
  • Increased liver enzymes
  • Nausea
  • Peripheral neuropathy (tingling and numbness of feet and hand)

How to use Twinculor 450mg/300mg Tablet:

Administer Twinculor 450mg/300mg tablets precisely as directed by your physician, adhering to the prescribed dosage and treatment duration. Ingest the tablet whole; avoid chewing, crushing, or fracturing it. Consume this medication on an empty stomach. Refrain from consuming Twinculor 450mg/300mg tablets concurrently with foods high in tyramine, including aged cheeses, cured meats, smoked fish, and certain beers.

How Twinculor 450mg/300mg Tablet works:

Combiflam-TB, a 450mg/300mg tablet containing Rifampicin and Isoniazid, combats tuberculosis (TB) infection. Rifampicin disables a crucial bacterial enzyme (RNA polymerase), halting TB's protein synthesis and replication. Concurrently, Isoniazid interferes with the bacteria's protective cell wall formation. This synergistic action eradicates the TB bacteria and resolves the infection.

SAFETY ADVICE

AlcoholAlcoholUNSAFE

Ingestion of alcohol during Twinculor 450mg/300mg Tablet use can lead to adverse effects including facial redness, rapid pulse, queasiness, dehydration, pectoral discomfort, and hypotension (a Disulfiram-like reaction).

PregnancyPregnancyCONSULT YOUR DOCTOR

The use of Twinculor 450mg/300mg tablets during pregnancy may pose risks. While human data is scarce, animal research indicates potential harm to the unborn child. A physician will assess the advantages against possible dangers prior to prescribing. Seek medical advice.

Breast feedingBreast feedingSAFE IF PRESCRIBED

The 450mg/300mg Twinculor tablet is considered safe for use while breastfeeding. Research in humans indicates negligible transfer of the medication into breast milk, posing no known risk to the infant.

DrivingDrivingUNSAFE

Driving ability may be impaired by Twinculor 450mg/300mg Tablets, which can induce seizures, psychiatric disorders, and optic neuritis (optic nerve inflammation potentially resulting in vision loss).

KidneyKidneyCAUTION

Patients with kidney disease should exercise caution when using Twinculor 450mg/300mg tablets. Dosage modifications for Twinculor 450mg/300mg tablets may be necessary. Physician consultation is advised.

LiverLiverCAUTION

Patients with liver impairment should exercise caution when using Twinculor 450mg/300mg tablets, as dosage modification may be necessary. Physician consultation is advised. Twinculor 450mg/300mg tablets are contraindicated in patients exhibiting severe hepatic dysfunction.

What if you forget to take Twinculor 450mg/300mg Tablet :

Should you forget a Twinculor 450mg/300mg Tablet dose, administer it promptly. Nevertheless, if your next scheduled dose is imminent, omit the missed dose and resume your usual dosing regimen. Avoid taking a double dose.

Facts to Know About Twinculor 450mg/300mg Tablet

LabelValue
Developing Habits No.
Treatment Category Anti-Infective Agents

FAQs on Twinculor 450mg/300mg Tablet

Twinculor 450mg/300mg tablets combine rifampicin and isoniazid to treat tuberculosis. Rifampicin disables a crucial bacterial enzyme (RNA polymerase), halting protein synthesis and bacterial reproduction. Isoniazid prevents the tuberculosis bacteria from building a protective shell. This combined action eliminates the bacteria and cures the infection.
Follow your prescribed medication regimen precisely; do not discontinue it prematurely, even if you feel improved. Refrain from alcohol consumption during treatment, as it increases the risk of liver damage. Report any vision changes, appetite loss, fatigue, stomach pain, nausea, vomiting, jaundice (yellowing of skin or eyes), or dark urine to your doctor immediately.
Follow your doctor's instructions precisely when taking Twinculor 450mg/300mg tablets. For best results, take the medication on an empty stomach, either one hour before or two hours after eating.
Twinculor 450mg/300mg Tablets may temporarily turn your urine, skin, sweat, saliva, tears, and feces brownish-red or orange. This is harmless.
Twinculor 450mg/300mg tablets can reduce the effectiveness of birth control pills. Therefore, discuss alternative, hormone-free birth control options with your doctor, such as condoms, diaphragms, and spermicides.
Store this medication in its original, tightly closed container, following the storage instructions on the label. Discard any unused medication; keep it out of reach of children, pets, and others.
Twinculor 450mg/300mg Tab...
58
MRP 68
14% off