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Votrient 400mg Tablet

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Glaxo SmithKline Pharmaceuticals Ltd

Salt Composition

Pazopanib (400mg)

Overview Votrient 400mg Tablet

Pazopanib 400mg tablets, a targeted therapy inhibiting protein kinases, are indicated for kidney cancer and soft-tissue sarcoma. Optimal absorption requires administration on an empty stomach, consistently at the same time daily. Dosage and frequency are determined by your physician based on your condition and may be adjusted. Strict adherence to the prescribed regimen is crucial, as incorrect use or overdose can lead to severe adverse reactions. Therapeutic effects may take weeks or months to manifest; discontinue only under your doctor's direction. Common side effects include elevated blood pressure and diarrhea. Regular blood pressure monitoring is often recommended, and increased fluid intake or medical consultation is advised for diarrhea. This medication can lower blood cell counts, increasing infection risk; report fever, flu-like symptoms, or breathlessness immediately. Prior to commencing treatment, disclose any pre-existing heart, liver, or kidney conditions, and all other medications, including anti-infectives, as drug interactions are possible. This medication is contraindicated in pregnancy and lactation; reliable contraception is essential for both partners throughout treatment.

Uses of Votrient 400mg Tablet

Renal cell carcinoma and soft tissue sarcoma

Major Benefits of Votrient 400mg Tablet:

Follow your doctor's instructions precisely regarding dosage and treatment length for this medication. Ingest the 400mg Votrient tablet whole; avoid crushing, chewing, or breaking it. Administer on an empty stomach.

Common Side effects of Votrient 400mg Tablet:

  • Headache
  • Nausea
  • Vomiting
  • Musculoskeletal (bone, muscle or joint) pain
  • Fatigue
  • Change in color of hair
  • Diarrhea
  • High blood pressure
  • Decreased appetite
  • Weight loss
  • Taste change
  • Abnormal skin pigmentation
  • Hair discoloration
  • Tumor pain
  • Breathlessness

How to use Votrient 400mg Tablet:

Consume this medication precisely as your physician directs, adhering to both the prescribed dosage and treatment length. Ingest the tablet whole; avoid chewing, crushing, or fracturing it. Administer Votrient 400mg tablets on an empty stomach.

How Votrient 400mg Tablet works:

Pazopanib 400mg tablets are an anticancer drug targeting tyrosine kinase receptors. By binding to these receptors, it blocks their activity, thus hindering the uncontrolled multiplication of cancer cells. Additionally, it prevents the formation of new blood vessels that nourish the tumor, thereby limiting its growth and spread.

SAFETY ADVICE

AlcoholAlcoholCONSULT YOUR DOCTOR

Alcohol consumption alongside Votrient 400mg Tablets may pose unknown risks. Seek medical advice before combining them.

PregnancyPregnancyCONSULT YOUR DOCTOR

Using Votrient 400mg tablets during pregnancy poses a confirmed risk to the fetus. Therefore, it's contraindicated except in exceptional, life-threatening circumstances where the potential benefits outweigh the known hazards. Always seek medical advice.

Breast feedingBreast feedingUNSAFE

Breastfeeding is contraindicated while taking Votrient 400mg tablets due to the potential for infant toxicity.

DrivingDrivingUNSAFE

Taking a 400mg Votrient tablet can cause drowsiness, blurred vision, and dizziness. Driving should be avoided if these effects are experienced.

KidneyKidneySAFE IF PRESCRIBED

Patients with kidney disease can safely take Votrient 400mg tablets without requiring a dosage change.

LiverLiverCAUTION

Patients with liver impairment should use 400mg Votrient tablets cautiously, potentially requiring dosage modification. Physician consultation is recommended. Votrient 400mg tablets are contraindicated for individuals with moderate to severe hepatic dysfunction.

What if you forget to take Votrient 400mg Tablet :

NA

Facts to Know About Votrient 400mg Tablet

LabelValue
Chemical Type Diarylalkylamines
Developing Habits No.
Treatment Category Cancer Medications
Actions Kinase inhibitors targeting tyrosine

FAQs on Votrient 400mg Tablet

Votrient 400mg tablets are not a standard chemotherapy drug; they're a protein kinase inhibitor. This medication functions by blocking proteins that promote cancer cell growth and spread.
Take one 400mg Votrient tablet orally once daily, or as your doctor instructs. Swallow the tablet whole with water; do not crush or break it, as this alters absorption and may increase side effects.
Take Votrient 400mg tablets on an empty stomach, at least one hour before or two hours after eating. Taking it with food may necessitate a higher dose, potentially increasing side effects.
Treatment duration with Votrient 400mg Tablet is individualized. Your doctor will determine the appropriate treatment length based on your response and tolerance, and you should not discontinue use without their guidance. Continue taking it as directed for as long as it remains effective and well-tolerated.
To maximize the effectiveness of your Votrient 400mg Tablet, avoid grapefruit and grapefruit juice, as they can interfere with its absorption. Consult your doctor regarding other potential dietary restrictions.
Treatment duration with Votrient 400mg Tablet is individualized. Your doctor will determine the appropriate treatment length based on your response and tolerance, and you should not discontinue use without consulting them. Continue taking the medication as directed for as long as it remains effective and well-tolerated.
Votrient 400mg tablets can cause serious or life-threatening liver damage. Report any history of liver disease to your doctor. Immediately contact your doctor if you experience symptoms like jaundice (yellowing skin or eyes), dark urine, fatigue, nausea, vomiting, appetite loss, upper right abdominal pain, or unusual bleeding/bruising. Pre-treatment liver tests may be required, followed by tests at weeks 3, 5, 7, and 9, and months 3 and 4. Further testing may be needed; ongoing monitoring will continue after 4 months.
Votrient 400mg Tablet
14,258
MRP 17,370
17% off