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Votrient 400mg Tablet

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Glaxo SmithKline Pharmaceuticals Ltd

Salt Composition

Pazopanib (400mg)

Overview Votrient 400mg Tablet

Pazopanib 400mg tablets, a tyrosine kinase inhibitor, treat kidney cancer and soft-tissue sarcoma. For optimal absorption, take this medication on an empty stomach, consistently at the same time daily. Dosage and frequency are determined by your physician based on your condition and may adjust over time; adhere strictly to their instructions. Incorrect usage or overdose can lead to severe adverse reactions. Therapeutic effects might take weeks or months to manifest; discontinue only under your doctor's guidance. Common side effects include elevated blood pressure and diarrhea. Your doctor may recommend regular blood pressure checks. Manage diarrhea with increased fluid intake or consult your physician if it worsens. This medication can lower blood cell counts, increasing infection risk. Report fever, flu-like symptoms, or shortness of breath immediately. Inform your doctor of pre-existing heart, liver, or kidney conditions, and all other medications, including antibiotics, as drug interactions are possible. Avoid pregnancy during treatment; reliable contraception is essential for both partners. A patient assistance program is available in India through Tata 1mg; contact your doctor or call (1800-102-1618) for details.

Uses of Votrient 400mg Tablet

Renal cell carcinoma and soft tissue sarcoma

Major Benefits of Votrient 400mg Tablet:

Consume this medication precisely as your physician directs, adhering to the prescribed dosage and timeframe. Ingest the tablet whole; avoid chewing, crushing, or fracturing it. Administer Votrient 400mg Tablet on an empty stomach.

Common Side effects of Votrient 400mg Tablet:

  • Headache
  • Nausea
  • Vomiting
  • Musculoskeletal (bone, muscle or joint) pain
  • Fatigue
  • Change in color of hair
  • Diarrhea
  • High blood pressure
  • Decreased appetite
  • Weight loss
  • Taste change
  • Abnormal skin pigmentation
  • Hair discoloration
  • Tumor pain
  • Breathlessness

How to use Votrient 400mg Tablet:

Consume this medication precisely as prescribed by your physician, adhering to both the dosage and treatment length. Ingest the tablet whole; avoid chewing, crushing, or fracturing it. Administer Votrient 400mg Tablet on an empty stomach.

How Votrient 400mg Tablet works:

Pazopanib 400mg tablets are a cancer treatment that functions by selectively targeting and blocking tyrosine kinase enzyme receptors, thus hindering the uncontrolled multiplication of malignant cells. The medication also suppresses angiogenesis, the formation of new blood vessels that nourish tumors, thereby limiting cancer growth.

SAFETY ADVICE

AlcoholAlcoholCONSULT YOUR DOCTOR

Alcohol consumption alongside Votrient 400mg tablets may pose safety risks; therefore, physician consultation is advised.

PregnancyPregnancyCONSULT YOUR DOCTOR

Using Votrient 400mg tablets during pregnancy poses a confirmed risk to the fetus. While generally contraindicated, a physician might exceptionally prescribe it in life-threatening circumstances where potential benefits outweigh the known hazards. Physician consultation is essential.

Breast feedingBreast feedingUNSAFE

Breastfeeding while taking Votrient 400mg tablets is contraindicated due to potential infant toxicity. Studies indicate a risk of harm to the nursing infant.

DrivingDrivingUNSAFE

Taking a 400mg Votrient tablet can cause drowsiness, blurred vision, and dizziness. Refrain from driving if you experience these effects.

KidneyKidneySAFE IF PRESCRIBED

Pazopanib 400mg tablets are suitable for use in patients exhibiting renal impairment. No alteration of the pazopanib 400mg tablet dosage is advised.

LiverLiverCAUTION

Patients with liver impairment should use 400mg Votrient tablets cautiously, potentially requiring dosage modification. Physician consultation is recommended. Votrient 400mg tablets are contraindicated for individuals with moderate to severe hepatic dysfunction.

What if you forget to take Votrient 400mg Tablet :

NA

Facts to Know About Votrient 400mg Tablet

LabelValue
Chemical Type Diarylalkylamines
Developing Habits No.
Treatment Category Cancer Medications
Actions Kinase inhibitors targeting tyrosine

FAQs on Votrient 400mg Tablet

Votrient 400mg tablets are not a traditional chemotherapy drug; they're a protein kinase inhibitor. This medication blocks the activity of proteins crucial to cancer cell growth and spread.
Take one 400mg Votrient tablet orally once daily, or as your doctor instructs. Swallow the tablet whole with water; do not crush or break it, as this alters absorption and may increase side effects.
Take Votrient 400mg tablets on an empty stomach, at least one hour before or two hours after eating. Taking it with food may require a higher dose, potentially increasing side effects.
Treatment duration with Votrient 400mg Tablet is individualized. Your doctor will determine the appropriate treatment length based on your response and tolerance. Never discontinue use without consulting your doctor. Continue taking it as long as it remains beneficial and well-tolerated.
To maximize the effectiveness of your Votrient 400mg Tablet, avoid grapefruit and grapefruit juice, as they can interfere with its absorption. Consult your doctor regarding other potential dietary restrictions.
Treatment duration with Votrient 400mg Tablet is individualized. Your doctor will determine the appropriate treatment length based on your response and tolerance. Never discontinue Votrient 400mg Tablet without consulting your doctor.
Votrient 400mg tablets can cause serious, potentially life-threatening liver damage. Report any history of liver disease to your doctor. Immediately contact your doctor if you experience symptoms like yellowing skin or eyes, dark urine, fatigue, nausea, vomiting, appetite loss, upper right abdominal pain, or unusual bleeding/bruising. Pre-treatment liver tests may be required, followed by tests at weeks 3, 5, 7, and 9, and months 3 and 4. Further testing may be needed; ongoing monitoring will continue after 4 months.
Votrient 400mg Tablet
14,258
MRP 17,370
17% off