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Xtern GP 0.5mg/500mg Tablet

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Prescription Required

Marketer

Ckris Laboratories Pvt Ltd

Salt Composition

Glimepiride (0.5mg) + Metformin (500mg)

Overview Xtern GP 0.5mg/500mg Tablet

Combiflex DM 0.5mg/500mg tablets are classified as antidiabetic agents, combining two medications for adult type 2 diabetes management. This treatment helps regulate blood sugar. Combiflex DM 0.5mg/500mg tablets should be ingested with food, consistently at the same time daily for optimal efficacy. Dosage is determined by your physician and may be adjusted based on your blood glucose readings. Continuous use is crucial, even with controlled blood sugar, as discontinuation without medical guidance risks elevated glucose levels, potentially leading to kidney complications, vision impairment, neuropathy, and limb loss. This medication is one component of a comprehensive diabetes management plan, including a balanced diet, regular physical activity, and weight management as directed by your doctor. Lifestyle choices significantly impact diabetes control. Hypoglycemia (low blood sugar) is a common side effect, characterized by symptoms like sweating, dizziness, headache, and tremors. Prompt glucose intake (e.g., sugary foods, juice) is essential; maintain regular meals and carry a fast-acting glucose source. Alcohol consumption should be minimized due to its hypoglycemic risk. Additional potential side effects include altered taste, nausea, diarrhea, abdominal discomfort, headache, and upper respiratory infections. Weight gain may occur. This medication is contraindicated in type 1 diabetes, diabetic ketoacidosis, and severe hepatic or renal impairment. Prior heart disease should be disclosed to your doctor before commencing treatment. Pregnant or lactating individuals require medical consultation before use. Regular blood glucose monitoring and periodic blood tests (blood cell counts and liver function) are recommended.

Uses of Xtern GP 0.5mg/500mg Tablet

Managing type 2 diabetes

Major Benefits of Xtern GP 0.5mg/500mg Tablet:

Consume this medication precisely as your physician directs, adhering to the prescribed dosage and treatment period. Ingest the Xtern GP 0.5mg/500mg tablet whole; avoid chewing, crushing, or fracturing it. Administer this medication with a meal.

Common Side effects of Xtern GP 0.5mg/500mg Tablet:

  • Headache
  • Hypoglycemia (low blood glucose level)
  • Nausea
  • Diarrhea

How to use Xtern GP 0.5mg/500mg Tablet:

Consume this medication precisely as your physician directs, adhering to the prescribed dosage and treatment schedule. Ingest the entire tablet without chewing, crushing, or breaking it. The Xtern GP 0.5mg/500mg tablet should be administered with a meal.

How Xtern GP 0.5mg/500mg Tablet works:

Xtern GP, a 0.5mg/500mg tablet, combines the antidiabetic agents glimepiride and metformin. Glimepiride, a sulfonylurea, stimulates pancreatic insulin release to reduce blood sugar. Metformin, a biguanide, acts by decreasing hepatic glucose production, slowing intestinal glucose uptake, and enhancing insulin responsiveness.

SAFETY ADVICE

AlcoholAlcoholUNSAFE

Combining Xtern GP 0.5mg/500mg Tablet and alcohol is unsafe.

PregnancyPregnancyCONSULT YOUR DOCTOR

Use of Xtern GP 0.5mg/500mg tablets during pregnancy may pose risks. While human data is scarce, animal studies indicate potential harm to the fetus. A physician will assess the potential benefits against these risks prior to prescription. Seek medical advice before taking this medication.

Breast feedingBreast feedingUNSAFE

Lactation is contraindicated with Xtern GP 0.5mg/500mg tablets due to the potential for infant toxicity.

DrivingDrivingCAUTION

Driving ability can be impaired by both hypoglycemia and hyperglycemia. Refrain from driving if such symptoms arise.

KidneyKidneyCAUTION

Patients with kidney impairment should use Xtern GP 0.5mg/500mg tablets cautiously, potentially requiring dosage modification. Physician consultation is advised. In cases of severe kidney disease, Xtern GP 0.5mg/500mg tablets are contraindicated. Routine kidney function monitoring is recommended during treatment.

LiverLiverCAUTION

Patients with liver impairment should use Xtern GP 0.5mg/500mg tablets cautiously, potentially requiring dosage modification. A physician's consultation is advised. For those with mild to moderate liver disease, initiation with a low dose is typical; however, it's contraindicated in cases of severe hepatic dysfunction.

What if you forget to take Xtern GP 0.5mg/500mg Tablet :

Should you forget to take your Xtern GP 0.5mg/500mg Tablet, administer it promptly. Nevertheless, if your next scheduled dose is imminent, omit the missed dose and resume your usual dosing regimen. Avoid taking a double dose.

Facts to Know About Xtern GP 0.5mg/500mg Tablet

LabelValue
Developing Habits No.
Treatment Category Diabetes Management

FAQs on Xtern GP 0.5mg/500mg Tablet

Store this medication in its original, tightly closed container, as directed on the label. Dispose of any unused medication properly and keep it out of reach of children, pets, and others.
Xtern GP 0.5mg/500mg Tablets can cause lactic acidosis, a serious medical emergency characterized by excessive blood lactic acid (also known as MALA, or Metformin-associated lactic acidosis). This rare but potentially harmful side effect is more likely in patients with kidney disease, the elderly, or those who consume significant amounts of alcohol. Symptoms include muscle pain or weakness, dizziness, fatigue, cold extremities, shortness of breath, nausea, vomiting, abdominal pain, and bradycardia. If you experience these symptoms, discontinue use and seek immediate medical attention.
Xtern GP 0.5mg/500mg tablets combine glimepiride and metformin to manage type 2 diabetes mellitus (DM) in adults. This medication improves blood glucose control when used with diet and exercise. Glimepiride stimulates insulin release from the pancreas, while metformin reduces liver glucose production and enhances insulin sensitivity. This combination is unsuitable for type 1 DM.
Xtern GP 0.5mg/500mg Tablets may cause common side effects such as hypoglycemia, altered taste, nausea, stomach pain, diarrhea, and headache. Rare but serious side effects, including lactic acidosis, are also possible. Prolonged use may result in vitamin B12 deficiency.
Prolonged use of Xtern GP 0.5mg/500mg Tablets can lead to Vitamin B12 deficiency by hindering its absorption in the stomach. This deficiency may cause anemia, nerve damage (manifested as tingling, numbness in extremities, weakness, and gait instability), urinary issues, and cognitive changes. To mitigate these risks, supplemental Vitamin B12 is recommended annually by some researchers.
Xtern GP 0.5mg/500mg Tablets can cause low blood sugar (hypoglycemia), manifesting as nausea, headache, irritability, hunger, sweating, dizziness, rapid heartbeat, anxiety, or shakiness. This risk increases with missed meals, alcohol consumption, excessive exercise, or concurrent use of other diabetes medications. Regular blood sugar monitoring is crucial. Carry a fast-acting sugar source, such as glucose tablets, honey, or fruit juice.
Combining Xtern GP 0.5mg/500mg Tablet with alcohol is unsafe. This combination may cause dangerously low blood sugar (hypoglycemia) and increase the risk of lactic acidosis.
Xtern GP 0.5mg/500mg Tabl...
34
MRP 42
19% off